2. Metabolic Enzyme/Protease Anti-infection
  3. Enolase Bacterial Antibiotic
  4. SF2312 ammonium

SF2312 ammonium is the ammonium form of SF2312. SF2312 is a phosphonate antibiotic and enolase inhibitor. SF2312 can be isolated from actinomycete Micromonospora, which is active under anaerobic conditions. SF2312 is selectively toxic to ENO1-deleted glioma cells.

For research use only. We do not sell to patients.

SF2312 ammonium Chemical Structure

SF2312 ammonium Chemical Structure

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Other Forms of SF2312 ammonium:

SF2312 ammonium Related Antibodies

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Description

SF2312 ammonium is the ammonium form of SF2312. SF2312 is a phosphonate antibiotic and enolase inhibitor. SF2312 can be isolated from actinomycete Micromonospora, which is active under anaerobic conditions. SF2312 is selectively toxic to ENO1-deleted glioma cells[1].

Molecular Weight

214.11

Formula

C4H11N2O6P
Appearance

Solid

Color

White to off-white

SMILES

O=C1N(C(CC1P(O)(O)=O)O)O.N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : ≥ 30 mg/mL (140.11 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6705 mL 23.3525 mL 46.7050 mL
5 mM 0.9341 mL 4.6705 mL 9.3410 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (246 KB) HNMR (515 KB) LCMS (86 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.6705 mL 23.3525 mL 46.7050 mL 116.7624 mL
5 mM 0.9341 mL 4.6705 mL 9.3410 mL 23.3525 mL
10 mM 0.4670 mL 2.3352 mL 4.6705 mL 11.6762 mL
15 mM 0.3114 mL 1.5568 mL 3.1137 mL 7.7842 mL
20 mM 0.2335 mL 1.1676 mL 2.3352 mL 5.8381 mL
25 mM 0.1868 mL 0.9341 mL 1.8682 mL 4.6705 mL
30 mM 0.1557 mL 0.7784 mL 1.5568 mL 3.8921 mL
40 mM 0.1168 mL 0.5838 mL 1.1676 mL 2.9191 mL
50 mM 0.0934 mL 0.4670 mL 0.9341 mL 2.3352 mL
60 mM 0.0778 mL 0.3892 mL 0.7784 mL 1.9460 mL
80 mM 0.0584 mL 0.2919 mL 0.5838 mL 1.4595 mL
100 mM 0.0467 mL 0.2335 mL 0.4670 mL 1.1676 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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SF2312 ammonium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SF2312SF 2312SF-2312EnolaseBacterialAntibioticPhosphopyruvate hydrataseInhibitorinhibitorinhibit

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