2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. SGC-UBD253

SGC-UBD253 is a potent HDAC6-UBD antagonist. SGC-UBD253 can be used in research of cancer.

For research use only. We do not sell to patients.

SGC-UBD253 Chemical Structure

SGC-UBD253 Chemical Structure

Size Price Stock Quantity
1 mg USD 164 In-stock
5 mg USD 410 In-stock
10 mg   Get quote  
50 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

SGC-UBD253 Related Antibodies

Top Publications Citing Use of Products

View All HDAC Isoform Specific Products:

View All Isoforms
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

SGC-UBD253 is a potent HDAC6-UBD antagonist. SGC-UBD253 can be used in research of cancer[1].

Molecular Weight

429.85

Formula

C21H20ClN3O5
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCC(N1CC(NCC2=CC=CC=C2OC)=O)=NC3=C(C=CC=C3Cl)C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (23.26 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3264 mL 11.6320 mL 23.2639 mL
5 mM 0.4653 mL 2.3264 mL 4.6528 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.3%

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3264 mL 11.6320 mL 23.2639 mL 58.1598 mL
5 mM 0.4653 mL 2.3264 mL 4.6528 mL 11.6320 mL
10 mM 0.2326 mL 1.1632 mL 2.3264 mL 5.8160 mL
15 mM 0.1551 mL 0.7755 mL 1.5509 mL 3.8773 mL
20 mM 0.1163 mL 0.5816 mL 1.1632 mL 2.9080 mL
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SGC-UBD253 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SGC-UBD253HDACHistone deacetylasesInhibitorinhibitorinhibit

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