2. Membrane Transporter/Ion Channel
  3. SGLT
  4. SGL5213

SGL5213 is a potent, oral active and low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor, with IC50 values of 29 nM and 20 nM for hSGLT1 and hSGLT2, respectively. SGL5213 has potential to treat type 2 diabetes treatment.

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SGL5213 Chemical Structure

SGL5213 Chemical Structure

CAS No. : 1240305-17-2

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SGL5213 Related Antibodies

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Description

SGL5213 is a potent, oral active and low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor, with IC50 values of 29 nM and 20 nM for hSGLT1 and hSGLT2, respectively. SGL5213 has potential to treat type 2 diabetes treatment[1].

IC50 & Target

IC50: 29nM/20 nM (hSGLT1/ hSGLT2)[1].
Molecular Weight

669.85

Formula

C37H55N3O8
CAS No.
SMILES

COC1=C([C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)C=C(CC3=CC=C(/C=C/C(C)(C)C(NC(C)(C)C(NCCN(C)C)=O)=O)C=C3)C(C(C)C)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SGL5213 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SGL52131240305-17-2SGL 5213SGL-5213SGLTSodium-dependent glucose cotransportersInhibitorinhibitorinhibit

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