2. Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. Src FAK EGFR
  4. Si306

Si306 is a Src inhibitor with antitumor activity. Si306 reduces the phosphorylation of focal adhesion kinase (FAK) and the expression of epidermal growth factor receptor (EGFR), and inhibits the invasion of human glioblastoma (GBM).

For research use only. We do not sell to patients.

Si306 Chemical Structure

Si306 Chemical Structure

CAS No. : 1640012-88-9

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Si306 Related Antibodies

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Lck Fyn Blk

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EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

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Description

Si306 is a Src inhibitor with antitumor activity. Si306 reduces the phosphorylation of focal adhesion kinase (FAK) and the expression of epidermal growth factor receptor (EGFR), and inhibits the invasion of human glioblastoma (GBM)[1].

Molecular Weight

573.94

Formula

C25H26BrClN6OS
CAS No.
SMILES

BrC1=CC(NC2=NC(SCCN3CCOCC3)=NC4=C2C=NN4CC(Cl)C5=CC=CC=C5)=CC=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Si306 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Si3061640012-88-9Si 306Si-306SrcFAKEGFRPTK2 protein tyrosine kinase 2PTK2Focal adhesion kinaseEpidermal growth factor receptorErbB-1HER1InhibitorAnti-tumorGBMInvasioninhibitorinhibit

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