2. Cell Cycle/DNA Damage Epigenetics
  3. Sirtuin
  4. SIRT-IN-6

SIRT-IN-6 (Compound 14) is a pan-inhibitor of SIRT1/2/3 with IC50 values of >50 μM. SIRT-IN-6 is promising for research of metabolic, inflammatory, oncologic and neurodegenerative disorders.

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SIRT-IN-6 Chemical Structure

SIRT-IN-6 Chemical Structure

CAS No. : 1431411-18-5

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SIRT-IN-6 Related Antibodies

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Description

SIRT-IN-6 (Compound 14) is a pan-inhibitor of SIRT1/2/3 with IC50 values of >50 μM. SIRT-IN-6 is promising for research of metabolic, inflammatory, oncologic and neurodegenerative disorders[1].

IC50 & Target

SIRT1

>50 μM (IC50)

SIRT2

>50 μM (IC50)

SIRT3

>50 μM (IC50)

Molecular Weight

213.64

Formula

C7H4ClN3OS
CAS No.
SMILES

O=C(C1=CC2=C(C(Cl)=NC=N2)S1)N
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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SIRT-IN-6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SIRT-IN-61431411-18-5SirtuinSIRT 1/2/3metabolicinflammatoryoncologic and neurodegenerative disordersInhibitorinhibitorinhibit

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