2. Cell Cycle/DNA Damage Epigenetics
  3. Sirtuin
  4. Sirtuin modulator 3

Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative, acts as a sirtuin modulator.

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Sirtuin modulator 3 Chemical Structure

Sirtuin modulator 3 Chemical Structure

CAS No. : 708995-11-3

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 55 In-stock
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid
5 mg USD 50 In-stock
10 mg USD 80 In-stock
25 mg USD 150 In-stock
50 mg USD 240 In-stock
100 mg USD 380 In-stock
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Description

Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative, acts as a sirtuin modulator[1].

Molecular Weight

417.46

Formula

C24H23N3O4
CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

C12C=C(C=CN1C=C(C1=CC=CC(=C1)NC(=O)C1C=C(OC)C(OC)=C(OC)C=1)N=2)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (598.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3954 mL 11.9772 mL 23.9544 mL
5 mM 0.4791 mL 2.3954 mL 4.7909 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.32%

COA (250 KB) HNMR (260 KB) LCMS (271 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3954 mL 11.9772 mL 23.9544 mL 59.8860 mL
5 mM 0.4791 mL 2.3954 mL 4.7909 mL 11.9772 mL
10 mM 0.2395 mL 1.1977 mL 2.3954 mL 5.9886 mL
15 mM 0.1597 mL 0.7985 mL 1.5970 mL 3.9924 mL
20 mM 0.1198 mL 0.5989 mL 1.1977 mL 2.9943 mL
25 mM 0.0958 mL 0.4791 mL 0.9582 mL 2.3954 mL
30 mM 0.0798 mL 0.3992 mL 0.7985 mL 1.9962 mL
40 mM 0.0599 mL 0.2994 mL 0.5989 mL 1.4971 mL
50 mM 0.0479 mL 0.2395 mL 0.4791 mL 1.1977 mL
60 mM 0.0399 mL 0.1996 mL 0.3992 mL 0.9981 mL
80 mM 0.0299 mL 0.1497 mL 0.2994 mL 0.7486 mL
100 mM 0.0240 mL 0.1198 mL 0.2395 mL 0.5989 mL
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Sirtuin modulator 3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sirtuin modulator 3708995-11-3Sirtuin modulator3Sirtuin modulator-3SirtuinN-phenyl benzamidecell lifespanagingstressdiabetesobesityneurodegenerative diseasescardiovascular diseaseblood clotting disordersinflammationcancerInhibitorinhibitorinhibit

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