2. Anti-infection
  3. Antibiotic Bacterial
  4. Sisomicin

Sisomicin  (Synonyms: Antibiotic 6640; Rickamicin)

Cat. No.: HY-B1222A Purity: 98.45%
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Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria.

For research use only. We do not sell to patients.

Sisomicin Chemical Structure

Sisomicin Chemical Structure

CAS No. : 32385-11-8

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Based on 5 publication(s) in Google Scholar

Other Forms of Sisomicin:

Sisomicin Related Antibodies

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Description

Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria[1][2].

IC50 & Target

Aminoglycoside

 

In Vitro

Sisomicin (6.25 μg/mL) completely inhibits the growth of various clinical isolates bacterial, such as Klebsiella, Salmonella, Citrobacter, and Staphylococcus aureus[1].
Sisomicin (20 μg/mL; 30 min) has insignificant impairment on polymorphonuclear neutrophil (PMN)[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sisomicin Related Antibodies
In Vivo

Sisomicin (4 mg/kg; ip; single dose) appears to accumulate and persist in the kidneys, showing potential renal toxicity in rats[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

447.53

Formula

C19H37N5O7
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O[C@@H]([C@@H]1O[C@@]2([H])OC(CN)=CC[C@H]2N)[C@H]([C@@H](C[C@@H]1N)N)O[C@](OC[C@](C)(O)[C@@H]3NC)([H])[C@@H]3O
Structure Classification
Initial Source

Micromonospora grisea
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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Sisomicin Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sisomicin32385-11-8Antibiotic 6640 RickamicinAntibiotic6640Antibiotic-6640AntibioticBacterialInhibitorinhibitorinhibit

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