SKF 77434 hydrobromide

Cat. No.: HY-103417 Purity: 99.2%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

SKF 77434 hydrobromide is a selective dopamine D1 receptor partial agonist. SKF 77434 hydrobromide has the potential to study cocaine addiction.

For research use only. We do not sell to patients.

SKF 77434 hydrobromide Chemical Structure

CAS No. : 300561-58-4

Size	Price	Stock	Quantity
5 mg	USD 123	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Dopamine Receptor D₁ Receptor D₂ Receptor D₃ Receptor D₄ Receptor D₅ Receptor

Biological Activity
Purity & Documentation
References
Customer Review

Description

SKF 77434 hydrobromide is a selective dopamine D1 receptor partial agonist. SKF 77434 hydrobromide has the potential to study cocaine addiction^[1].

Molecular Weight

376.29

Formula

C₁₉H₂₂BrNO₂

CAS No.

300561-58-4

Appearance

Solid

Color

White to off-white

SMILES

OC1=C(O)C=C2C(C3=CC=CC=C3)CN(CC=C)CCC2=C1.Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 38 mg/mL (100.99 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6575 mL	13.2876 mL	26.5752 mL
5 mM	0.5315 mL	2.6575 mL	5.3150 mL
10 mM	0.2658 mL	1.3288 mL	2.6575 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.2%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (253 KB)

Handling Instructions (2659 KB)

References

[1]. Cohen C, et al. Effects of D1 dopamine receptor agonists on oral ethanol self-administration in rats: comparison with their efficacy to produce grooming and hyperactivity. Psychopharmacology (Berl). 1999 Feb;142(1):102-10. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6575 mL	13.2876 mL	26.5752 mL	66.4381 mL
	5 mM	0.5315 mL	2.6575 mL	5.3150 mL	13.2876 mL
	10 mM	0.2658 mL	1.3288 mL	2.6575 mL	6.6438 mL
	15 mM	0.1772 mL	0.8858 mL	1.7717 mL	4.4292 mL
	20 mM	0.1329 mL	0.6644 mL	1.3288 mL	3.3219 mL
	25 mM	0.1063 mL	0.5315 mL	1.0630 mL	2.6575 mL
	30 mM	0.0886 mL	0.4429 mL	0.8858 mL	2.2146 mL
	40 mM	0.0664 mL	0.3322 mL	0.6644 mL	1.6610 mL
	50 mM	0.0532 mL	0.2658 mL	0.5315 mL	1.3288 mL
	60 mM	0.0443 mL	0.2215 mL	0.4429 mL	1.1073 mL
	80 mM	0.0332 mL	0.1661 mL	0.3322 mL	0.8305 mL
	100 mM	0.0266 mL	0.1329 mL	0.2658 mL	0.6644 mL