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  4. Smilagenin acetate

Smilagenin acetate is a sapogenin derivative extracted from patent US20030004147A1. Smilagenin acetate increases the expression of acetylcholine m2 receptors and can be used for the research of dementia.

For research use only. We do not sell to patients.

Smilagenin acetate Chemical Structure

Smilagenin acetate Chemical Structure

CAS No. : 4947-75-5

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Based on 1 publication(s) in Google Scholar

Smilagenin acetate Related Antibodies

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Description

Smilagenin acetate is a sapogenin derivative extracted from patent US20030004147A1. Smilagenin acetate increases the expression of acetylcholine m2 receptors and can be used for the research of dementia[1].

In Vitro

Smilagenin acetate increases the expression of m2 receptors on CHO cells transfected with DNA for the m2 receptor[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Smilagenin acetate Related Antibodies
Molecular Weight

458.67

Formula

C29H46O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]3([H])[C@@](C[C@@]1([H])[C@@]4([H])[C@]([C@@]5([C@](C[C@H](CC5)OC(C)=O)([H])CC4)C)([H])CC2)([H])O[C@]6(CC[C@H](CO6)C)[C@H]3C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

Ethanol : 10 mg/mL (21.80 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1802 mL 10.9011 mL 21.8022 mL
5 mM 0.4360 mL 2.1802 mL 4.3604 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 2.1802 mL 10.9011 mL 21.8022 mL 54.5054 mL
5 mM 0.4360 mL 2.1802 mL 4.3604 mL 10.9011 mL
10 mM 0.2180 mL 1.0901 mL 2.1802 mL 5.4505 mL
15 mM 0.1453 mL 0.7267 mL 1.4535 mL 3.6337 mL
20 mM 0.1090 mL 0.5451 mL 1.0901 mL 2.7253 mL
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Smilagenin acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Smilagenin4947-75-5OtherssapogenindementiacognitivedisfunctionInhibitorinhibitorinhibit

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