2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. SNPB

SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).

For research use only. We do not sell to patients.

SNPB Chemical Structure

SNPB Chemical Structure

CAS No. : 663598-85-4

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5 mg USD 55 In-stock
10 mg USD 95 In-stock
25 mg USD 190 In-stock
50 mg USD 310 In-stock
100 mg USD 500 In-stock
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Based on 1 publication(s) in Google Scholar

SNPB Related Antibodies

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Description

SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).

IC50 & Target[1]

Disulfide Cleavable Linker

 

Cleavable Linker

 

Molecular Weight

371.39

Formula

C13H13N3O6S2
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(ON1C(CCC1=O)=O)CCCSSC2=NC=C([N+]([O-])=O)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (269.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6926 mL 13.4629 mL 26.9259 mL
5 mM 0.5385 mL 2.6926 mL 5.3852 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6926 mL 13.4629 mL 26.9259 mL 67.3147 mL
5 mM 0.5385 mL 2.6926 mL 5.3852 mL 13.4629 mL
10 mM 0.2693 mL 1.3463 mL 2.6926 mL 6.7315 mL
15 mM 0.1795 mL 0.8975 mL 1.7951 mL 4.4876 mL
20 mM 0.1346 mL 0.6731 mL 1.3463 mL 3.3657 mL
25 mM 0.1077 mL 0.5385 mL 1.0770 mL 2.6926 mL
30 mM 0.0898 mL 0.4488 mL 0.8975 mL 2.2438 mL
40 mM 0.0673 mL 0.3366 mL 0.6731 mL 1.6829 mL
50 mM 0.0539 mL 0.2693 mL 0.5385 mL 1.3463 mL
60 mM 0.0449 mL 0.2244 mL 0.4488 mL 1.1219 mL
80 mM 0.0337 mL 0.1683 mL 0.3366 mL 0.8414 mL
100 mM 0.0269 mL 0.1346 mL 0.2693 mL 0.6731 mL
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SNPB Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SNPB663598-85-4ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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