2. Metabolic Enzyme/Protease Neuronal Signaling
  3. FAAH
  4. Sob-AM2

Sob-AM2 is a potent substrate targeting fatty acid amide hydrolase (FAAH) expressed in the brain (Km=1.3 μM), delivering high concentrations of Sobetirome (HY-14823) to the central nervous system with minimal peripheral systemic dose, thereby stimulating central thyroid hormone receptor β (TRβ).

For research use only. We do not sell to patients.

Sob-AM2 Chemical Structure

Sob-AM2 Chemical Structure

CAS No. : 2128258-47-7

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5 mg USD 400 In-stock
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Based on 1 publication(s) in Google Scholar

Sob-AM2 Related Antibodies

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Description

Sob-AM2 is a potent substrate targeting fatty acid amide hydrolase (FAAH) expressed in the brain (Km=1.3 μM), delivering high concentrations of Sobetirome (HY-14823) to the central nervous system with minimal peripheral systemic dose, thereby stimulating central thyroid hormone receptor β (TRβ)[1].

Molecular Weight

341.44

Formula

C21H27NO3
CAS No.
Appearance

Solid

SMILES

O=C(COC1=CC(C)=C(CC2=CC=C(C(C(C)C)=C2)O)C(C)=C1)NC
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (58.58 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9288 mL 14.6439 mL 29.2877 mL
5 mM 0.5858 mL 2.9288 mL 5.8575 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9288 mL 14.6439 mL 29.2877 mL 73.2193 mL
5 mM 0.5858 mL 2.9288 mL 5.8575 mL 14.6439 mL
10 mM 0.2929 mL 1.4644 mL 2.9288 mL 7.3219 mL
15 mM 0.1953 mL 0.9763 mL 1.9525 mL 4.8813 mL
20 mM 0.1464 mL 0.7322 mL 1.4644 mL 3.6610 mL
25 mM 0.1172 mL 0.5858 mL 1.1715 mL 2.9288 mL
30 mM 0.0976 mL 0.4881 mL 0.9763 mL 2.4406 mL
40 mM 0.0732 mL 0.3661 mL 0.7322 mL 1.8305 mL
50 mM 0.0586 mL 0.2929 mL 0.5858 mL 1.4644 mL
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Sob-AM2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sob-AM22128258-47-7FAAHFatty acid amide hydrolaseBlood-brain permeabilityeffective substratecentral nervous systemthyroid hormone receptorInhibitorinhibitorinhibit

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