Sodium 3-methyl-2-oxobutanoate-¹³C₄,d₄

Name: Sodium 3-methyl-2-oxobutanoate- 13 C 4 ,d 4
Brand: MedChemExpress
SKU: HY-W006057AS2
Rating: 4.5 (1 reviews)

Cat. No.: HY-W006057AS2 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Sodium 3-methyl-2-oxobutanoate-¹³C₄,d₄ is the deuterium and ¹³C labeled Sodium 3-methyl-2-oxobutanoate[1].

For research use only. We do not sell to patients.

Sodium 3-methyl-2-oxobutanoate-<sup>13</sup>C<sub>4</sub>,d<sub>4</sub> Chemical Structure

Sodium 3-methyl-2-oxobutanoate-¹³C₄,d₄ Chemical Structure

CAS No. : 1185115-88-1

Size	Price	Stock	Quantity
5 mg	USD 170	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 275	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 550	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Other Forms of Sodium 3-methyl-2-oxobutanoate-¹³C₄,d₄:

Sodium 3-methyl-2-oxobutanoate Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Sodium 3-methyl-2-oxobutanoate-¹³C₄,d₄ is the deuterium and ¹³C labeled Sodium 3-methyl-2-oxobutanoate[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

146.09

Formula

C¹³C₄H₃D₄NaO₃

CAS No.

1185115-88-1

Unlabeled CAS

3715-29-5

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([13C]([13CH3])([13C]([13C](O[Na])=O)=O)[2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

H₂O : 250 mg/mL (1711.27 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.8451 mL	34.2255 mL	68.4510 mL
5 mM	1.3690 mL	6.8451 mL	13.6902 mL
10 mM	0.6845 mL	3.4225 mL	6.8451 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (252 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.8451 mL	34.2255 mL	68.4510 mL	171.1274 mL
	5 mM	1.3690 mL	6.8451 mL	13.6902 mL	34.2255 mL
	10 mM	0.6845 mL	3.4225 mL	6.8451 mL	17.1127 mL
	15 mM	0.4563 mL	2.2817 mL	4.5634 mL	11.4085 mL
	20 mM	0.3423 mL	1.7113 mL	3.4225 mL	8.5564 mL
	25 mM	0.2738 mL	1.3690 mL	2.7380 mL	6.8451 mL
	30 mM	0.2282 mL	1.1408 mL	2.2817 mL	5.7042 mL
	40 mM	0.1711 mL	0.8556 mL	1.7113 mL	4.2782 mL
	50 mM	0.1369 mL	0.6845 mL	1.3690 mL	3.4225 mL
	60 mM	0.1141 mL	0.5704 mL	1.1408 mL	2.8521 mL
	80 mM	0.0856 mL	0.4278 mL	0.8556 mL	2.1391 mL
	100 mM	0.0685 mL	0.3423 mL	0.6845 mL	1.7113 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.