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Soluflazine is a nucleoside transport inhibitor with anticonvulsant action. Soluflazine can be used as an antiepileptic agent.

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Soluflazine Chemical Structure

Soluflazine Chemical Structure

CAS No. : 112415-83-5

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Based on 1 publication(s) in Google Scholar

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Description

Soluflazine is a nucleoside transport inhibitor with anticonvulsant action. Soluflazine can be used as an antiepileptic agent[1].

Molecular Weight

631.40

Formula

C28H32Cl4FN5O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1=C(Cl)C=CC=C1Cl)CN2CC(C(N)=O)N(CCCC(C3=CC=C(F)C=C3)C4=CC=CN=C4)CC2.[H]Cl.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (197.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 83.33 mg/mL (131.98 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5838 mL 7.9189 mL 15.8378 mL
5 mM 0.3168 mL 1.5838 mL 3.1676 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 1.5838 mL 7.9189 mL 15.8378 mL 39.5946 mL
5 mM 0.3168 mL 1.5838 mL 3.1676 mL 7.9189 mL
10 mM 0.1584 mL 0.7919 mL 1.5838 mL 3.9595 mL
15 mM 0.1056 mL 0.5279 mL 1.0559 mL 2.6396 mL
20 mM 0.0792 mL 0.3959 mL 0.7919 mL 1.9797 mL
25 mM 0.0634 mL 0.3168 mL 0.6335 mL 1.5838 mL
30 mM 0.0528 mL 0.2640 mL 0.5279 mL 1.3198 mL
40 mM 0.0396 mL 0.1980 mL 0.3959 mL 0.9899 mL
50 mM 0.0317 mL 0.1584 mL 0.3168 mL 0.7919 mL
60 mM 0.0264 mL 0.1320 mL 0.2640 mL 0.6599 mL
80 mM 0.0198 mL 0.0990 mL 0.1980 mL 0.4949 mL
100 mM 0.0158 mL 0.0792 mL 0.1584 mL 0.3959 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Soluflazine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Soluflazine112415-83-5OthersInhibitorinhibitorinhibit

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