1. Others
  2. Others
  3. Sontigidomide

Sontigidomide (Compound 5) is an antineoplastic compound. Sontigidomide inhibits MOLM-13 cell proliferation more than 80% at 1 μM (3 days).

For research use only. We do not sell to patients.

Sontigidomide Chemical Structure

Sontigidomide Chemical Structure

CAS No. : 2560577-69-5

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Sontigidomide (Compound 5) is an antineoplastic compound. Sontigidomide inhibits MOLM-13 cell proliferation more than 80% at 1 μM (3 days)[1].

Molecular Weight

513.47

Formula

C26H22F3N3O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C(C1=CC=C(C2(C(F)(F)F)CC2)C=C1)=O)NCC3=CC=C4C(N(C5C(NC(CC5)=O)=O)CC4=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (243.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9475 mL 9.7377 mL 19.4753 mL
5 mM 0.3895 mL 1.9475 mL 3.8951 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.62%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9475 mL 9.7377 mL 19.4753 mL 48.6883 mL
5 mM 0.3895 mL 1.9475 mL 3.8951 mL 9.7377 mL
10 mM 0.1948 mL 0.9738 mL 1.9475 mL 4.8688 mL
15 mM 0.1298 mL 0.6492 mL 1.2984 mL 3.2459 mL
20 mM 0.0974 mL 0.4869 mL 0.9738 mL 2.4344 mL
25 mM 0.0779 mL 0.3895 mL 0.7790 mL 1.9475 mL
30 mM 0.0649 mL 0.3246 mL 0.6492 mL 1.6229 mL
40 mM 0.0487 mL 0.2434 mL 0.4869 mL 1.2172 mL
50 mM 0.0390 mL 0.1948 mL 0.3895 mL 0.9738 mL
60 mM 0.0325 mL 0.1623 mL 0.3246 mL 0.8115 mL
80 mM 0.0243 mL 0.1217 mL 0.2434 mL 0.6086 mL
100 mM 0.0195 mL 0.0974 mL 0.1948 mL 0.4869 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Sontigidomide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Sontigidomide
Cat. No.:
HY-156641
Quantity:
MCE Japan Authorized Agent: