Spermidine-alkyne trihydrochloride

Cat. No.: HY-170757A: FAQs
Data Sheet Handling Instructions Technical Support

Spermidine-alkyne trihydrochloride is a Spermidine (HY-B1776) derivative endowed with an alkyne handle. Spermidine-alkyne trihydrochloride is a Spermidine probe, which can be used for the determination of the Spermidine binding to cellular proteins.

For research use only. We do not sell to patients.

Spermidine-alkyne trihydrochloride Chemical Structure

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This product is a controlled substance and not for sale in your territory.

Other Forms of Spermidine-alkyne trihydrochloride:

Spermidine-alkyne Get quote

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

292.68

Formula

C₁₀H₂₄Cl₃N₃

Appearance

Solid

SMILES

C#CCNCCCCNCCCN.Cl.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (341.67 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4167 mL	17.0835 mL	34.1670 mL
5 mM	0.6833 mL	3.4167 mL	6.8334 mL
10 mM	0.3417 mL	1.7084 mL	3.4167 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Singh VP, et al., Chemoproteomic Identification of Spermidine-Binding Proteins and Antitumor-Immunity Activators. J Am Chem Soc. 2024 Jun 7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.4167 mL	17.0835 mL	34.1670 mL	85.4175 mL
	5 mM	0.6833 mL	3.4167 mL	6.8334 mL	17.0835 mL
	10 mM	0.3417 mL	1.7084 mL	3.4167 mL	8.5418 mL
	15 mM	0.2278 mL	1.1389 mL	2.2778 mL	5.6945 mL
	20 mM	0.1708 mL	0.8542 mL	1.7084 mL	4.2709 mL
	25 mM	0.1367 mL	0.6833 mL	1.3667 mL	3.4167 mL
	30 mM	0.1139 mL	0.5695 mL	1.1389 mL	2.8473 mL
	40 mM	0.0854 mL	0.4271 mL	0.8542 mL	2.1354 mL
	50 mM	0.0683 mL	0.3417 mL	0.6833 mL	1.7084 mL
	60 mM	0.0569 mL	0.2847 mL	0.5695 mL	1.4236 mL
	80 mM	0.0427 mL	0.2135 mL	0.4271 mL	1.0677 mL
	100 mM	0.0342 mL	0.1708 mL	0.3417 mL	0.8542 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.