2. Immunology/Inflammation
  3. SphK
  4. SphK2-IN-3

SphK2-IN-3 (compound 12q) is a selective active sphingosine kinase-2 inhibitor. SphK2-IN-3 has anti-proliferative activity against various cancer cells, inducing G2 phase arrest and apoptosis in liver cancer cells HepG2.

For research use only. We do not sell to patients.

SphK2-IN-3 Chemical Structure

SphK2-IN-3 Chemical Structure

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SphK2-IN-3 Related Antibodies

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Description

SphK2-IN-3 (compound 12q) is a selective active sphingosine kinase-2 inhibitor. SphK2-IN-3 has anti-proliferative activity against various cancer cells, inducing G2 phase arrest and apoptosis in liver cancer cells HepG2[1].

Molecular Weight

471.38

Formula

C25H24Cl2N2O3
SMILES

ClC1=C(Cl)C=CC(COC2=CC=C(C3=CC=C(CC(N4CCC[C@H]4CO)=O)C=C3)C=N2)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SphK2-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SphK2-IN-3SphKSphingosine kinasesphingosine kinase-2anti-proliferativeG2 phaseapoptosisHepG2Inhibitorinhibitorinhibit

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HY-162580
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