2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. SQ 29548

SQ 29548, a high affinity radioligand, is a selective thromboxane-prostanoid (TP) receptor antagonist.

For research use only. We do not sell to patients.

SQ 29548 Chemical Structure

SQ 29548 Chemical Structure

CAS No. : 98672-91-4

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Based on 1 publication(s) in Google Scholar

SQ 29548 Related Antibodies

Top Publications Citing Use of Products

View All Prostaglandin Receptor Isoform Specific Products:

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DP EP FP IP TXA2/TP TXB2

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Description

SQ 29548, a high affinity radioligand, is a selective thromboxane-prostanoid (TP) receptor antagonist[1][2].

Molecular Weight

387.47

Formula

C21H29N3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1=CC=CC=C1)NNC[C@H]2[C@H]([C@H]3O[C@@H]2CC3)C/C=C\CCCC(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (12.90 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5808 mL 12.9042 mL 25.8084 mL
5 mM 0.5162 mL 2.5808 mL 5.1617 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5808 mL 12.9042 mL 25.8084 mL 64.5211 mL
5 mM 0.5162 mL 2.5808 mL 5.1617 mL 12.9042 mL
10 mM 0.2581 mL 1.2904 mL 2.5808 mL 6.4521 mL
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SQ 29548 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SQ 2954898672-91-4SQ29548SQ-29548Prostaglandin Receptoracute myocardial ischemiaAnti-ischemicThromboxane A2 receptorInhibitorinhibitorinhibit

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