2. Anti-infection
  3. SARS-CoV
  4. SSAA09E3

SSAA09E3 is a SARS-CoV entry inhibitor that inhibits SARS/HIV pseudotyped virus entry with an EC50 of 9.7 μM in 293T cells and inhibits SARS-CoV infection of Vero cells with an EC50 of 0.15 μM.

For research use only. We do not sell to patients.

SSAA09E3 Chemical Structure

SSAA09E3 Chemical Structure

CAS No. : 52869-18-8

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10 mg USD 130 In-stock
25 mg USD 250 In-stock
50 mg USD 400 In-stock
100 mg USD 650 In-stock
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Based on 1 publication(s) in Google Scholar

SSAA09E3 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

SSAA09E3 is a SARS-CoV entry inhibitor that inhibits SARS/HIV pseudotyped virus entry with an EC50 of 9.7 μM in 293T cells and inhibits SARS-CoV infection of Vero cells with an EC50 of 0.15 μM[1][2].

IC50 & Target

SARS-CoV[1]
Cellular Effect
Cell Line Type Value Description References
Vero CC50
20 μM
Compound: 32; SSAA09E3
Cytotoxicity against african green monkey Vero cells incubated for 3 days
Cytotoxicity against african green monkey Vero cells incubated for 3 days
[PMID: 32539378]
In Vitro

SSAA09E3 blocks viral entry by inhibiting fusion of the viral membrane with the host cell membrane[1].
SSAA09E3 inhibits later stages of viral entry[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SSAA09E3 Related Antibodies
Molecular Weight

327.33

Formula

C21H13NO3
CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

O=C(NC(C=C1C2=O)=CC=C1C(C3=C2C=CC=C3)=O)C4=CC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (101.82 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0550 mL 15.2751 mL 30.5502 mL
5 mM 0.6110 mL 3.0550 mL 6.1100 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0550 mL 15.2751 mL 30.5502 mL 76.3755 mL
5 mM 0.6110 mL 3.0550 mL 6.1100 mL 15.2751 mL
10 mM 0.3055 mL 1.5275 mL 3.0550 mL 7.6376 mL
15 mM 0.2037 mL 1.0183 mL 2.0367 mL 5.0917 mL
20 mM 0.1528 mL 0.7638 mL 1.5275 mL 3.8188 mL
25 mM 0.1222 mL 0.6110 mL 1.2220 mL 3.0550 mL
30 mM 0.1018 mL 0.5092 mL 1.0183 mL 2.5459 mL
40 mM 0.0764 mL 0.3819 mL 0.7638 mL 1.9094 mL
50 mM 0.0611 mL 0.3055 mL 0.6110 mL 1.5275 mL
60 mM 0.0509 mL 0.2546 mL 0.5092 mL 1.2729 mL
80 mM 0.0382 mL 0.1909 mL 0.3819 mL 0.9547 mL
100 mM 0.0306 mL 0.1528 mL 0.3055 mL 0.7638 mL
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SSAA09E3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SSAA09E352869-18-8SARS-CoVSARS coronavirusviral entry293T cellsVero cellsInhibitorinhibitorinhibit

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