2. Cell Cycle/DNA Damage Epigenetics
  3. PARP
  4. ST7710AA1

ST7710AA1 (compound 1l) is a potent PARP-1 inhibitor with an IC50 value of 0.07 µM. ST7710AA1 shows an antiproliferative activity. ST7710AA1 shows anticancer activity.

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ST7710AA1 Chemical Structure

ST7710AA1 Chemical Structure

CAS No. : 1542067-20-8

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ST7710AA1 Related Antibodies

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PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP7 PARP10 PARP14 PARP15 PARP12 PARP16

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Description

ST7710AA1 (compound 1l) is a potent PARP-1 inhibitor with an IC50 value of 0.07 µM. ST7710AA1 shows an antiproliferative activity. ST7710AA1 shows anticancer activity[1].

IC50 & Target[1]

PARP-1

0.07 μM (IC50)

In Vitro

ST7710AA1 (compound 1l) (0-200 µM; 72 h) shows antiproliferative with IC50s of 19.43, 22.04 µM for HCC1937, Capan 1, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ST7710AA1 Related Antibodies
In Vivo

ST7710AA1 (100 mg/kg; i.p.; every 2 days for 2 weeks) shows antitumor activity in mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

334.41

Formula

C20H22N4O
CAS No.
SMILES

O=C(N1C=CC2=C1N=C(C=C2)C3=CC=C(C=C3)CN4CCCCC4)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ST7710AA1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ST7710AA11542067-20-8PARPpoly ADP ribose polymeraseHCC1937Capan 1antiproliferativeanticancerInhibitorinhibitorinhibit

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