1. Apoptosis Metabolic Enzyme/Protease
  2. Caspase Drug Metabolite
  3. VRT-043198 (Standard)

VRT-043198 (Standard) is the analytical standard of VRT-043198. This product is intended for research and analytical applications. VRT-043198, the agent metabolite of VX-765 (Belnacasan), is a potent, selective and blood-brain barrier permeable inhibitor of interleukin-converting enzyme/caspase-1 subfamily caspases. VRT-043198 exhibits Ki values of 0.8 nM and 0.6 nM for ICE/caspase-1 and caspase-4, respectively[1].

For research use only. We do not sell to patients.

VRT-043198 (Standard) Chemical Structure

VRT-043198 (Standard) Chemical Structure

CAS No. : 244133-31-1

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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VRT-043198 (Standard)
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HY-112226R
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