Starburst 1st generation (Synonyms: PAMAM G1.0)

Cat. No.: HY-169474: FAQs
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Starburst 1st Generation (PAMAM G1.0) is a Polyamidoamine (HY-164657; PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vitro. Starburst 1st Generation conjugated to di-n-dodecylamine and encapsulating 5-Fluorouracil (HY-90006) increase the solubility of 5-Fluorouracil and are cytotoxic to AGS gastric adenocarcinoma cells.

For research use only. We do not sell to patients.

Starburst 1st generation Chemical Structure

CAS No. : 142986-44-5

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Description	Starburst 1st Generation (PAMAM G1.0) is a Polyamidoamine (HY-164657; PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vitro. Starburst 1st Generation conjugated to di-n-dodecylamine and encapsulating 5-Fluorouracil (HY-90006) increase the solubility of 5-Fluorouracil and are cytotoxic to AGS gastric adenocarcinoma cells^[1].
Molecular Weight	1429.85
Formula	C₆₂H₁₂₈N₂₆O₁₂
CAS No.	142986-44-5
SMILES	O=C(CCN(CCC(NCCN)=O)CCNC(CCN(CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)=O)NCCN
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (267 KB) Handling Instructions (2659 KB)
References	[1]. Ender Sarigul, et al. Polyamidoamine Dendron-Bearing Lipids as Drug-Delivery Excipients. Molecules. 2022 Nov 13;27(22):7817. [Content Brief]

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Starburst 1st generation142986-44-5PAMAM G1.0Biochemical Assay ReagentsInhibitorinhibitorinhibit

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Starburst 1st generation (Synonyms: PAMAM G1.0)

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