1. JAK/STAT Signaling Stem Cell/Wnt
  2. STAT
  3. STAT3-IN-29

STAT3-IN-29 (Compound B20) is an inhibitor for STAT3. STAT3-IN-29 inhibits the proliferation of HaCaT cell with IC50 of 0.09 µM, ameliorates the IMQ-induced psoriasis in mouse models.

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STAT3-IN-29 Chemical Structure

STAT3-IN-29 Chemical Structure

CAS No. : 2256751-16-1

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Description

STAT3-IN-29 (Compound B20) is an inhibitor for STAT3. STAT3-IN-29 inhibits the proliferation of HaCaT cell with IC50 of 0.09 µM, ameliorates the IMQ-induced psoriasis in mouse models[1].

IC50 & Target

STAT3

 

Molecular Weight

365.34

Formula

C20H15NO6

CAS No.
SMILES

COC(C=C1)=C(OC)C=C1CC2=NOC3=C2C(C4=C(O)C=CC=C4C3=O)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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STAT3-IN-29 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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STAT3-IN-29
Cat. No.:
HY-161864
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