2. JAK/STAT Signaling Stem Cell/Wnt
  3. STAT
  4. STAT3-IN-41

STAT3-IN-41 (Compound 16) is a prodrug of compound 1. STAT3-IN-41 slowly releases compound 1 inhibiting STAT3 signaling pathway. STAT3-IN-41 shows antitumor activity against lung cancer, hepatocellular carcinoma and pancreatic cancer.

For research use only. We do not sell to patients.

STAT3-IN-41 Chemical Structure

STAT3-IN-41 Chemical Structure

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STAT3-IN-41 Related Antibodies

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STAT3 STAT5 STAT6 STAT1

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Description

STAT3-IN-41 (Compound 16) is a prodrug of compound 1. STAT3-IN-41 slowly releases compound 1 inhibiting STAT3 signaling pathway. STAT3-IN-41 shows antitumor activity against lung cancer, hepatocellular carcinoma and pancreatic cancer[1].

IC50 & Target[1]

STAT3

 

Molecular Weight

477.47

Formula

C22H30F3NO7
SMILES

O=C1O[C@@H]2[C@H](O3)[C@@]3(C)CC/C=C(CC(F)(F)F)\CC[C@H]2[C@@H]1CN(C)C.OC(/C=C/C(O)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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STAT3-IN-41 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

STAT3-IN-41STATantitumor activitylung cancerhepatocellular carcinoma and pancreatic cancerNCI–H820Huh-7and PANC1Inhibitorinhibitorinhibit

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