2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. StRIP16

StRIP16, bioavailable StRIP3 analogue, is a double-stapled peptide which can bind to Rab8a GTPase, with a Kd of 12.7 μM.

For research use only. We do not sell to patients.

StRIP16 Chemical Structure

StRIP16 Chemical Structure

CAS No. : 2761279-63-2

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StRIP16 Related Antibodies

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Description

StRIP16, bioavailable StRIP3 analogue, is a double-stapled peptide which can bind to Rab8a GTPase, with a Kd of 12.7 μM[1].

IC50 & Target

Kd: 12.7 μM (Rab8a GTPase)[1]
In Vitro

StRIP16 shows selectivity for Rab8 over other Rab-GTPases and does not engage H-Ras or N-Ras (rel. Kd=~10, ~25, ~35, 1.0, ~10, >100, >50, and >100 for Rab1b, Rab5a, Rab6a, Rab8a, Rab9a, Rab11a, H- and N-Ras respectively)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

StRIP16 Related Antibodies
Molecular Weight

2300.65

Formula

C116H154N24O26
CAS No.
SMILES

CC(C)C[C@H](NC([C@H](CC1=CN=CN1)NC([C@H](CC2=CC=C(O)C=C2)NC([C@]3(C)CCC/C=C/CCC[C@](C(N[C@@H](CCC(N)=O)C(N[C@@H](CC4=CNC5=CC=CC=C45)C(N[C@@H](CC6=CC=CC=C6)C(N3)=O)=O)=O)=O)(C)NC([C@H](CCC(O)=O)NC([C@H](CC(N)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O)=O)=O)=O)=O)=O)C(N[C@@]7(C)CCC/C=C/CCC[C@](C(N[C@@H](C(C)C)C(N)=O)=O)(C)NC([C@H](CC(N)=O)NC([C@H](CC8=CC=CC=C8)NC([C@H](CC9=CC=CC=C9)NC7=O)=O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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StRIP16 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

StRIP162761279-63-2StRIP 16StRIP-16RasStRIP3double-stapledRab8aGTPaseInhibitorinhibitorinhibit

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