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  3. Suc-Leu-Tyr-AMC

Suc-Leu-Tyr-AMC is a fluorometric peptide substrate for µ-calpain and m-calpain. The excitation wavelength is 360 nm and the emission wavelength is 460 nm.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Suc-Leu-Tyr-AMC Chemical Structure

Suc-Leu-Tyr-AMC Chemical Structure

CAS No. : 94367-20-1

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Based on 1 publication(s) in Google Scholar

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Description

Suc-Leu-Tyr-AMC is a fluorometric peptide substrate for µ-calpain and m-calpain. The excitation wavelength is 360 nm and the emission wavelength is 460 nm[1].

Molecular Weight

551.59

Formula

C29H33N3O8

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{Suc}-Leu-Tyr-{AMC}

Sequence Shortening

{Suc}-LY-{AMC}

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (181.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8129 mL 9.0647 mL 18.1294 mL
5 mM 0.3626 mL 1.8129 mL 3.6259 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8129 mL 9.0647 mL 18.1294 mL 45.3235 mL
5 mM 0.3626 mL 1.8129 mL 3.6259 mL 9.0647 mL
10 mM 0.1813 mL 0.9065 mL 1.8129 mL 4.5324 mL
15 mM 0.1209 mL 0.6043 mL 1.2086 mL 3.0216 mL
20 mM 0.0906 mL 0.4532 mL 0.9065 mL 2.2662 mL
25 mM 0.0725 mL 0.3626 mL 0.7252 mL 1.8129 mL
30 mM 0.0604 mL 0.3022 mL 0.6043 mL 1.5108 mL
40 mM 0.0453 mL 0.2266 mL 0.4532 mL 1.1331 mL
50 mM 0.0363 mL 0.1813 mL 0.3626 mL 0.9065 mL
60 mM 0.0302 mL 0.1511 mL 0.3022 mL 0.7554 mL
80 mM 0.0227 mL 0.1133 mL 0.2266 mL 0.5665 mL
100 mM 0.0181 mL 0.0906 mL 0.1813 mL 0.4532 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Suc-Leu-Tyr-AMC
Cat. No.:
HY-135172
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