Succinic anhydride-¹³C₂

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Succinic anhydride-¹³C₂ is the ¹³C labeled Succinic anhydride[1]. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[2].

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Succinic anhydride-<sup>13</sup>C<sub>2</sub> Chemical Structure

Succinic anhydride-¹³C₂ Chemical Structure

CAS No. : 67519-25-9

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1 mg		Get quote	Estimated Time of Arrival: December 31

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Other Forms of Succinic anhydride-¹³C₂:

Succinic anhydride Get quote

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Description	Succinic anhydride-¹³C₂ is the ¹³C labeled Succinic anhydride[1]. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[2].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Succinic anhydride-¹³C₂ Related Antibodies
Molecular Weight	102.06
Formula	C₂¹³C₂H₄O₃
CAS No.	67519-25-9
Unlabeled CAS	108-30-5
SMILES	O=[13C]1O[13C](CC1)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief] [2]. Dale Boger.et al. Chimer containing a targeting portion linked to a scission-activated duocarmycin-type prodrug. WO2009064913A1.