Sulfameter-¹³C₆  (Synonyms: Sulfametoxydiazine-¹³C₆; 5-Methoxysulfadiazine-¹³C₆)

Sulfameter-¹³C₆ is the ¹³C₆ labeled Sulfameter. Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

286.26

C₅¹³C₆H₁₂N₄O₃S

651-06-9

N[13C]1=[13CH][13CH]=[13C]([13CH]=[13CH]1)S(NC2=NC=C(C=N2)OC)(=O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Kaumeier S. The effect of the composition of food on the absorption of sulfameter. Int J Clin Pharmacol Biopharm. 1979 Jun;17(6):260-3.  [Content Brief]

  [3]. Douglas H.Nakahata, et al. Crystal structure, spectroscopic characterization and antibacterial activities of a silver complex with sulfameter. Journal of Molecular Structure. Volume 1125, 5 December 2016, Pages 609-615