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  3. Sulfathiazole-d4

Sulfathiazole-d4 is a deuterium labeled Sulfathiazole. Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish.

For research use only. We do not sell to patients.

Sulfathiazole-d<sub>4</sub> Chemical Structure

Sulfathiazole-d4 Chemical Structure

CAS No. : 1020719-89-4

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Description

Sulfathiazole-d4 is a deuterium labeled Sulfathiazole. Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish[1][2][3][4].

Molecular Weight

259.34

Formula

C9H5D4N3O2S2

CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=C([2H])C([2H])=C(N)C([2H])=C1[2H])(NC2=NC=CS2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.90%

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Sulfathiazole-d4
Cat. No.:
HY-B0507S
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