2. Anti-infection
  3. Bacterial Antibiotic
  4. Sulfathiazole

Sulfathiazole, an organosulfur compound, is used as a short-acting sulfonamide antibiotic.

For research use only. We do not sell to patients.

Sulfathiazole Chemical Structure

Sulfathiazole Chemical Structure

CAS No. : 72-14-0

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Based on 3 publication(s) in Google Scholar

Other Forms of Sulfathiazole:

Sulfathiazole Related Antibodies

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Description

Sulfathiazole, an organosulfur compound, is used as a short-acting sulfonamide antibiotic[1][2][3].

IC50 & Target

Antibacterial
Cellular Effect
Cell Line Type Value Description References
HepG2 IC50
4161 μM
Compound: 3a
Cytotoxicity against human HepG2 cells after 24 hrs by MTS assay
Cytotoxicity against human HepG2 cells after 24 hrs by MTS assay
[PMID: 22365879]
Sf9 IC50
430 μM
Compound: 19
Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity assay
Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity assay
[PMID: 26824386]
In Vitro

Sulfathiazole (20 μg/L) starts to be degraded between day 31 and day 38 in one of the two batch reactors containing different wastewater matrices. Sulfathiazole is degraded at a substantially faster rate than sulfamethoxazole or sulfamethazine in the nitrification process (S3)[1]. Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole has acidity constant of pKa of 7.1and retention times (tR) of 7.8. S/N values for Sulfathiazole are above 100 at the 1 mg/kg level[2]]. Sulfathiazole sorption to inorganic sorbents exhibits pronounced pH dependence consistent with sorbate speciation and sorbent charge properties. Sulfathiazole cations are most important for sorption to clay minerals, followed by neutral species[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sulfathiazole Related Antibodies
Molecular Weight

255.32

Formula

C9H9N3O2S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC=C(N)C=C1)(NC2=NC=CS2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (979.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9167 mL 19.5833 mL 39.1665 mL
5 mM 0.7833 mL 3.9167 mL 7.8333 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9167 mL 19.5833 mL 39.1665 mL 97.9163 mL
5 mM 0.7833 mL 3.9167 mL 7.8333 mL 19.5833 mL
10 mM 0.3917 mL 1.9583 mL 3.9167 mL 9.7916 mL
15 mM 0.2611 mL 1.3056 mL 2.6111 mL 6.5278 mL
20 mM 0.1958 mL 0.9792 mL 1.9583 mL 4.8958 mL
25 mM 0.1567 mL 0.7833 mL 1.5667 mL 3.9167 mL
30 mM 0.1306 mL 0.6528 mL 1.3056 mL 3.2639 mL
40 mM 0.0979 mL 0.4896 mL 0.9792 mL 2.4479 mL
50 mM 0.0783 mL 0.3917 mL 0.7833 mL 1.9583 mL
60 mM 0.0653 mL 0.3264 mL 0.6528 mL 1.6319 mL
80 mM 0.0490 mL 0.2448 mL 0.4896 mL 1.2240 mL
100 mM 0.0392 mL 0.1958 mL 0.3917 mL 0.9792 mL
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Sulfathiazole Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfathiazole72-14-0BacterialAntibioticsulfonamideantibioticbacteriaInhibitorinhibitorinhibit

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