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Surlorian is a ryanodine receptor (RyR) stabilizer.

For research use only. We do not sell to patients.

Surlorian Chemical Structure

Surlorian Chemical Structure

CAS No. : 1467605-57-7

Size Price Stock Quantity
5 mg USD 136 In-stock
10 mg USD 205 In-stock
25 mg USD 410 In-stock
50 mg USD 615 In-stock
100 mg USD 923 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Surlorian is a ryanodine receptor (RyR) stabilizer[1].

IC50 & Target

Ryanodine receptor, RyR[1]

Molecular Weight

329.41

Formula

C18H19NO3S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=C(CN2CC3=CC(OC)=CC=C3SCC2)C=C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (303.57 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0357 mL 15.1787 mL 30.3573 mL
5 mM 0.6071 mL 3.0357 mL 6.0715 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0357 mL 15.1787 mL 30.3573 mL 75.8933 mL
5 mM 0.6071 mL 3.0357 mL 6.0715 mL 15.1787 mL
10 mM 0.3036 mL 1.5179 mL 3.0357 mL 7.5893 mL
15 mM 0.2024 mL 1.0119 mL 2.0238 mL 5.0596 mL
20 mM 0.1518 mL 0.7589 mL 1.5179 mL 3.7947 mL
25 mM 0.1214 mL 0.6071 mL 1.2143 mL 3.0357 mL
30 mM 0.1012 mL 0.5060 mL 1.0119 mL 2.5298 mL
40 mM 0.0759 mL 0.3795 mL 0.7589 mL 1.8973 mL
50 mM 0.0607 mL 0.3036 mL 0.6071 mL 1.5179 mL
60 mM 0.0506 mL 0.2530 mL 0.5060 mL 1.2649 mL
80 mM 0.0379 mL 0.1897 mL 0.3795 mL 0.9487 mL
100 mM 0.0304 mL 0.1518 mL 0.3036 mL 0.7589 mL
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Surlorian Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Surlorian
Cat. No.:
HY-159502
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