1. Cell Cycle/DNA Damage
  2. Cyclin G-associated Kinase (GAK)
  3. TA-316 (GMP)

TA-316 (GMP)  (Synonyms: Megakaryocytes/platelets inducing agent (GMP))

Cat. No.: HY-112486G
Handling Instructions Technical Support

TA-316 (GMP) is TA-316 (HY-112486) produced by using GMP guidelines. GMP grade small molecules can be used as auxiliary agents in cell therapy. TA-316 is a c-MPL agonist and a thrombopoietin (TPO) receptor agonist.

For research use only. We do not sell to patients.

TA-316 (GMP) Chemical Structure

TA-316 (GMP) Chemical Structure

CAS No. : 1429321-13-0

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Based on 1 publication(s) in Google Scholar

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Description

TA-316 (GMP) is TA-316 (HY-112486) produced by using GMP guidelines. GMP grade small molecules can be used as auxiliary agents in cell therapy. TA-316 is a c-MPL agonist and a thrombopoietin (TPO) receptor agonist[1].

Molecular Weight

641.56

Formula

C28H25BrN4O5S2

CAS No.
Appearance

Solid

Color

Light yellow to brown

SMILES

O=C(C1=CC=C(C(NCC2=CC=C(C(NCCO)=O)C=C2)=O)S1)N/N=C(C3=CSC(C4=CC=C(Br)C=C4)=C3O)\C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (155.87 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5587 mL 7.7935 mL 15.5870 mL
5 mM 0.3117 mL 1.5587 mL 3.1174 mL
View the Complete Stock Solution Preparation Table
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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5587 mL 7.7935 mL 15.5870 mL 38.9675 mL
5 mM 0.3117 mL 1.5587 mL 3.1174 mL 7.7935 mL
10 mM 0.1559 mL 0.7794 mL 1.5587 mL 3.8968 mL
15 mM 0.1039 mL 0.5196 mL 1.0391 mL 2.5978 mL
20 mM 0.0779 mL 0.3897 mL 0.7794 mL 1.9484 mL
25 mM 0.0623 mL 0.3117 mL 0.6235 mL 1.5587 mL
30 mM 0.0520 mL 0.2598 mL 0.5196 mL 1.2989 mL
40 mM 0.0390 mL 0.1948 mL 0.3897 mL 0.9742 mL
50 mM 0.0312 mL 0.1559 mL 0.3117 mL 0.7794 mL
60 mM 0.0260 mL 0.1299 mL 0.2598 mL 0.6495 mL
80 mM 0.0195 mL 0.0974 mL 0.1948 mL 0.4871 mL
100 mM 0.0156 mL 0.0779 mL 0.1559 mL 0.3897 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
TA-316 (GMP)
Cat. No.:
HY-112486G
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