2. Cytoskeleton
  3. Integrin
  4. TAK-029

TAK-029 is a potent GP IIb/IIIa antagonist. TAK-029 has potent antithrombotic effects with bleeding time (BT) prolongation in arterial thrombosis models. TAK-029 can be used for the research of various arterial thrombotic diseases.

For research use only. We do not sell to patients.

TAK-029 Chemical Structure

TAK-029 Chemical Structure

CAS No. : 176655-58-6

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TAK-029 Related Antibodies

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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Description

TAK-029 is a potent GP IIb/IIIa antagonist. TAK-029 has potent antithrombotic effects with bleeding time (BT) prolongation in arterial thrombosis models. TAK-029 can be used for the research of various arterial thrombotic diseases[1].

In Vivo

在豚鼠中，TAK-029（30-100 μg/kg，静脉注射）可完全抑制 ADP 诱导的体外血小板聚集，并延长给药后的 BT[1]。
在狗中，TAK-029（30-100 μg/kg，静脉注射）可抑制 ADP 诱导的体外血小板聚集[1]。
在猴子中，TAK-029（10-30 μg/kg，静脉注射）可抑制 ADP 诱导的体外血小板聚集，并延长 BT[1]。

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

433.42

Formula

C19H23N5O7
CAS No.
SMILES

O=C(CNC(C1=CC=C(C(N)=N)C=C1)=O)N([C@H]2CC(OC)=O)CCN(CC(O)=O)C2=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TAK-029 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TAK-029176655-58-6TAK029TAK 029Integrinarterial thrombotic diseasesInhibitorinhibitorinhibit

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