1. Antibody-drug Conjugate/ADC Related Protein Tyrosine Kinase/RTK
  2. Antibody-Drug Conjugates (ADCs) c-Met/HGFR
  3. Telisotuzumab vedotin

Telisotuzumab vedotin  (Synonyms: ABBV-399)

Cat. No.: HY-141601 Purity: 99.90%
Handling Instructions Technical Support

Telisotuzumab vedotin (ABBV-399) is an antibody-drug conjugate (ADCs) targeting c-Met. Telisotuzumab vedotin consists of Monomethyl Auristatin E (MMAE), Telisotuzumab antibody and a cleavable mc-val-cit-PABC type linker. Telisotuzumab vedotin can be used to study non-small cell lung cancer expressing c-Met protein.

For research use only. We do not sell to patients.

Telisotuzumab vedotin Chemical Structure

Telisotuzumab vedotin Chemical Structure

CAS No. : 1714088-51-3

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Based on 1 publication(s) in Google Scholar

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Description

Telisotuzumab vedotin (ABBV-399) is an antibody-drug conjugate (ADCs) targeting c-Met. Telisotuzumab vedotin consists of Monomethyl Auristatin E (MMAE), Telisotuzumab antibody and a cleavable mc-val-cit-PABC type linker. Telisotuzumab vedotin can be used to study non-small cell lung cancer expressing c-Met protein[1][2].

Clinical Trial
Molecular Weight

145000 (average)

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Telisotuzumab vedotin]

Shipping

Shipping with dry ice.

Storage

-80°C, protect from light

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL

*"≥" means soluble, but saturation unknown.

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Purity & Documentation

Purity: 99.90%

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Telisotuzumab vedotin
Cat. No.:
HY-141601
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