2. Anti-infection
  3. HBV
  4. Tenofovir amibufenamide

Tenofovir amibufenamide  (Synonyms: HS-10234)

Cat. No.: HY-137453 Purity: 99.38% ee.: 99.42%
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Tenofovir amibufenamide (HS-10234), a Tenofovir prodrug, is an orally active antiviral agent. Tenofovir amibufenamide inhibits HBV, and can be used for chronic hepatitis B (CHB) study.

For research use only. We do not sell to patients.

Tenofovir amibufenamide Chemical Structure

Tenofovir amibufenamide Chemical Structure

CAS No. : 1571076-26-0

Size Price Stock Quantity
1 mg USD 280 In-stock
5 mg USD 700 In-stock
10 mg USD 1050 In-stock
25 mg USD 1680 In-stock
50 mg USD 2350 In-stock
100 mg USD 3200 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Tenofovir amibufenamide Related Antibodies

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Description

Tenofovir amibufenamide (HS-10234), a Tenofovir prodrug, is an orally active antiviral agent. Tenofovir amibufenamide inhibits HBV, and can be used for chronic hepatitis B (CHB) study[1][2].

Clinical Trial
Molecular Weight

490.49

Formula

C22H31N6O5P
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

C[C@@H](OC[P@](OC1=CC=CC=C1)(NC(C)(C)C(OC(C)C)=O)=O)CN2C3=NC=NC(N)=C3N=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (407.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0388 mL 10.1939 mL 20.3878 mL
5 mM 0.4078 mL 2.0388 mL 4.0776 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0388 mL 10.1939 mL 20.3878 mL 50.9694 mL
5 mM 0.4078 mL 2.0388 mL 4.0776 mL 10.1939 mL
10 mM 0.2039 mL 1.0194 mL 2.0388 mL 5.0969 mL
15 mM 0.1359 mL 0.6796 mL 1.3592 mL 3.3980 mL
20 mM 0.1019 mL 0.5097 mL 1.0194 mL 2.5485 mL
25 mM 0.0816 mL 0.4078 mL 0.8155 mL 2.0388 mL
30 mM 0.0680 mL 0.3398 mL 0.6796 mL 1.6990 mL
40 mM 0.0510 mL 0.2548 mL 0.5097 mL 1.2742 mL
50 mM 0.0408 mL 0.2039 mL 0.4078 mL 1.0194 mL
60 mM 0.0340 mL 0.1699 mL 0.3398 mL 0.8495 mL
80 mM 0.0255 mL 0.1274 mL 0.2548 mL 0.6371 mL
100 mM 0.0204 mL 0.1019 mL 0.2039 mL 0.5097 mL
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Tenofovir amibufenamide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tenofovir amibufenamide1571076-26-0HS-10234HS10234HS 10234HBVHepatitis B virusantiviralCHBtenofovirInhibitorinhibitorinhibit

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