2. PROTAC
  3. Ligands for E3 Ligase
  4. Tetrafluoro-thalidomide

Tetrafluoro-thalidomide is a fluorinated Thalidomide analogue. Tetrafluoro-thalidomide is an activator of E3 ligase, which ubiquitinylates proteins for later proteolysis. The structure may be further derivatized via substitution at its fluorines.

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Tetrafluoro-thalidomide Chemical Structure

Tetrafluoro-thalidomide Chemical Structure

CAS No. : 179033-21-7

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Tetrafluoro-thalidomide Related Antibodies

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View All Ligands for E3 Ligase Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1

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Description

Tetrafluoro-thalidomide is a fluorinated Thalidomide analogue. Tetrafluoro-thalidomide is an activator of E3 ligase, which ubiquitinylates proteins for later proteolysis. The structure may be further derivatized via substitution at its fluorines.

Molecular Weight

330.19

Formula

C13H6F4N2O4
CAS No.
SMILES

O=C1C2=C(C(N1C3C(NC(CC3)=O)=O)=O)C(F)=C(F)C(F)=C2F
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Tetrafluoro-thalidomide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tetrafluoro-thalidomide179033-21-7Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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