2. PI3K/Akt/mTOR
  3. PI3K
  4. TGX-155

TGX-155 (AZ12649385) is a selective inhibitor of PI3Kβ. TGX-155 has potential applications in antithrombotic therapy.

For research use only. We do not sell to patients.

TGX-155 Chemical Structure

TGX-155 Chemical Structure

CAS No. : 351071-90-4

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TGX-155 Related Antibodies

Top Publications Citing Use of Products

View All PI3K Isoform Specific Products:

View All Isoforms
PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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Description

TGX-155 (AZ12649385) is a selective inhibitor of PI3Kβ. TGX-155 has potential applications in antithrombotic therapy[1][2][3].

IC50 & Target[1]

PI3Kβ

 

In Vivo

TGX-155 (1.5 mg/kg and 2.5 mg/kg; i.v.; single dose) significantly improves the cyclic flow reductions (CFRs) in rabbit carotid artery injury in a time-dependent and dose-dependent manner[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

354.37

Formula

C20H19FN2O3
CAS No.
SMILES

O=C1C2=CC=CC(OC3=C(C=C(F)C=C3)C)=C2NC(N4CCOCC4)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TGX-155 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TGX-155351071-90-4AZ12649385TGX155TGX 155AZ 12649385AZ-12649385PI3KPhosphoinositide 3-kinaseRabbitCyclic flow reductionsCFRsInhibitorinhibitorinhibit

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