1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Thymine-d4

Thymine-d4 is the deuterium labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.

For research use only. We do not sell to patients.

Thymine-d<sub>4</sub> Chemical Structure

Thymine-d4 Chemical Structure

CAS No. : 200496-79-3

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Description

Thymine-d4 is the deuterium labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

130.14

Formula

C5H2D4N2O2

CAS No.
Unlabeled CAS

65-71-4

SMILES

O=C1C(C([2H])([2H])[2H])=C([2H])NC(N1)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Thymine-d4
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HY-W010450S
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