2. Natural Products
  3. Disease Research Fields Plants Terpenoids
  4. Euphorbiaceae Inflammation/Immunology Triterpenes
  5. Euphorbia boetica
  6. Tirucallol

Tirucallol, a tetracyclic triterpene, is isolated from Euphorbia lacteal latex. Tirucallol has topical anti-inflammatory effect. Tirucallol can suppress ear edema in the mouse model and inhibit nitrite production in lipopolysaccharide-stimulated macrophages.

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Tirucallol Chemical Structure

Tirucallol Chemical Structure

CAS No. : 514-46-5

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5 mg USD 260 In-stock
10 mg USD 420 In-stock
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Tirucallol Related Antibodies

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Description

Tirucallol, a tetracyclic triterpene, is isolated from Euphorbia lacteal latex. Tirucallol has topical anti-inflammatory effect. Tirucallol can suppress ear edema in the mouse model and inhibit nitrite production in lipopolysaccharide-stimulated macrophages[1].

Molecular Weight

426.72

Formula

C30H50O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12C3=C(CC[C@]1([C@](CC2)([H])[C@@H](C)CC/C=C(C)\C)C)[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC3)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (23.43 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3435 mL 11.7173 mL 23.4346 mL
5 mM 0.4687 mL 2.3435 mL 4.6869 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3435 mL 11.7173 mL 23.4346 mL 58.5864 mL
5 mM 0.4687 mL 2.3435 mL 4.6869 mL 11.7173 mL
10 mM 0.2343 mL 1.1717 mL 2.3435 mL 5.8586 mL
15 mM 0.1562 mL 0.7812 mL 1.5623 mL 3.9058 mL
20 mM 0.1172 mL 0.5859 mL 1.1717 mL 2.9293 mL
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Tirucallol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tirucallol514-46-5OtherstetracyclictriterpeneEuphorbialacteallatexantiinflammatoryInhibitorinhibitorinhibit

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