2. Neuronal Signaling
  3. OGA
  4. TP-040

TP-040  (Synonyms: O-GlcNAcase-IN-1)

Cat. No.: HY-131979 Purity: 98.59%
COA Handling Instructions

Molarity Calculator

TP-040 (O-GlcNAcase-IN-1) is a potent and novel OGA inhibitor with an IC50 value of 46 nM.

For research use only. We do not sell to patients.

TP-040 Chemical Structure

TP-040 Chemical Structure

CAS No. : 2757254-99-0

Size Price Stock Quantity
5 mg USD 90 In-stock
10 mg USD 160 In-stock
25 mg USD 340 In-stock
50 mg USD 580 In-stock
100 mg USD 980 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

TP-040 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

TP-040 (O-GlcNAcase-IN-1) is a potent and novel OGA inhibitor with an IC50 value of 46 nM.

Molecular Weight

286.38

Formula

C15H22N6
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CC1CCN(C2=NC(NCC3=CN(C)C=N3)=NC=C2)CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (87.30 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4919 mL 17.4593 mL 34.9186 mL
5 mM 0.6984 mL 3.4919 mL 6.9837 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.59%

COA (243 KB) HNMR (141 KB) RP-HPLC (190 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4919 mL 17.4593 mL 34.9186 mL 87.2966 mL
5 mM 0.6984 mL 3.4919 mL 6.9837 mL 17.4593 mL
10 mM 0.3492 mL 1.7459 mL 3.4919 mL 8.7297 mL
15 mM 0.2328 mL 1.1640 mL 2.3279 mL 5.8198 mL
20 mM 0.1746 mL 0.8730 mL 1.7459 mL 4.3648 mL
25 mM 0.1397 mL 0.6984 mL 1.3967 mL 3.4919 mL
30 mM 0.1164 mL 0.5820 mL 1.1640 mL 2.9099 mL
40 mM 0.0873 mL 0.4365 mL 0.8730 mL 2.1824 mL
50 mM 0.0698 mL 0.3492 mL 0.6984 mL 1.7459 mL
60 mM 0.0582 mL 0.2910 mL 0.5820 mL 1.4549 mL
80 mM 0.0436 mL 0.2182 mL 0.4365 mL 1.0912 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

TP-040 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TP-0402757254-99-0O-GlcNAcase-IN-1TP040TP 040OGAO-GlcNAc hydrolaseO-GlcNAcaseInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
TP-040
Cat. No.:
HY-131979
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.