2. Anti-infection
  3. HIV
  4. Trecovirsen

Trecovirsen (GEM91) is a 25-mer antisense phosphorothioate oligonucleotide targeted at the gag site of the HIV gene.

The free form of the compound is prone to instability, it is advisable to consider the stable salt form (Trecovirsen sodium) that retains the same biological activity.

For research use only. We do not sell to patients.

DNA, d(P-thio)(C-T-C-T-C-G-C-A-C-C-C-A-T-C-T-C-T-C-T-C-C-T-T-C-T)

Trecovirsen Chemical Structure

CAS No. : 153021-75-1

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5 mg USD 232 Ask For Quote & Lead Time
10 mg USD 345 Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

Other Forms of Trecovirsen:

Trecovirsen Related Antibodies

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Description

Trecovirsen (GEM91) is a 25-mer antisense phosphorothioate oligonucleotide targeted at the gag site of the HIV gene.

Molecular Weight

7776.30

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Trecovirsen]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 200 mg/mL (25.72 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.1286 mL 0.6430 mL 1.2860 mL
5 mM 0.0257 mL 0.1286 mL 0.2572 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.1286 mL 0.6430 mL 1.2860 mL 3.2149 mL
5 mM 0.0257 mL 0.1286 mL 0.2572 mL 0.6430 mL
10 mM 0.0129 mL 0.0643 mL 0.1286 mL 0.3215 mL
15 mM 0.0086 mL 0.0429 mL 0.0857 mL 0.2143 mL
20 mM 0.0064 mL 0.0321 mL 0.0643 mL 0.1607 mL
25 mM 0.0051 mL 0.0257 mL 0.0514 mL 0.1286 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Trecovirsen Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trecovirsen153021-75-1GEM91GEM 91GEM-91HIVHuman immunodeficiency virusInhibitorinhibitorinhibit

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