2. Anti-infection
  3. Fungal
  4. Triadimenol

Triadimenol is a triazole fungicide and has been widely used in agriculture. Triadimenol has certain toxicity to animals.

For research use only. We do not sell to patients.

Triadimenol Chemical Structure

Triadimenol Chemical Structure

CAS No. : 55219-65-3

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Based on 1 publication(s) in Google Scholar

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Description

Triadimenol is a triazole fungicide and has been widely used in agriculture. Triadimenol has certain toxicity to animals[1].

In Vivo

Triadimenol (6.25-125 μM; cultured for 48 h in rat serum) influences cranial nerve and ganglia in rat embryos[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 9.5 day-old Rat embryos[1]
Dosage: 6.25-125 μM
Administration: Cultured for 48 h in rat serum
Result: Showed specific cranial nerve and ganglia abnormalities.
Molecular Weight

295.76

Formula

C14H18ClN3O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC=C(OC(C(O)C(C)(C)C)N2N=CN=C2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 175 mg/mL (591.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3811 mL 16.9056 mL 33.8112 mL
5 mM 0.6762 mL 3.3811 mL 6.7622 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3811 mL 16.9056 mL 33.8112 mL 84.5280 mL
5 mM 0.6762 mL 3.3811 mL 6.7622 mL 16.9056 mL
10 mM 0.3381 mL 1.6906 mL 3.3811 mL 8.4528 mL
15 mM 0.2254 mL 1.1270 mL 2.2541 mL 5.6352 mL
20 mM 0.1691 mL 0.8453 mL 1.6906 mL 4.2264 mL
25 mM 0.1352 mL 0.6762 mL 1.3524 mL 3.3811 mL
30 mM 0.1127 mL 0.5635 mL 1.1270 mL 2.8176 mL
40 mM 0.0845 mL 0.4226 mL 0.8453 mL 2.1132 mL
50 mM 0.0676 mL 0.3381 mL 0.6762 mL 1.6906 mL
60 mM 0.0564 mL 0.2818 mL 0.5635 mL 1.4088 mL
80 mM 0.0423 mL 0.2113 mL 0.4226 mL 1.0566 mL
100 mM 0.0338 mL 0.1691 mL 0.3381 mL 0.8453 mL
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Triadimenol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Triadimenol55219-65-3Fungaldemethylationfungicytotoxicitycranial nervegangliaInhibitorinhibitorinhibit

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