Trifloxystrobin-d₆  (Synonyms: CGA 279202-d₆)

Trifloxystrobin-d₆ is the deuterium labeled Trifloxystrobin. Trifloxystrobin (CGA 279202) is a fungicide, with EC50s of 23.0 μg/L and 1.7 μg/L for Daphnia magna neonate and embryos, respectively, after treatment for 48 h[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

414.41

C₂₀H₁₃D₆F₃N₂O₄

2470226-50-5

141517-21-7

C/C(C1=CC(C(F)(F)F)=CC=C1)=N\OC([2H])([2H])C2=C(C([2H])=C([2H])C([2H])=C2[2H])/C(C(OC)=O)=N\OC

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief]

  [2]. Cui F, et al. Toxicity of three strobilurins (kresoxim-methyl, pyraclostrobin, and trifloxystrobin) on Daphnia magna. Environ Toxicol Chem. 2017 Jan;36(1):182-189.  [Content Brief]