Trifluperidol hydrochloride (Synonyms: R 2498)

Cat. No.: HY-124462 Purity: 99.4%: FAQs
Data Sheet SDS COA Handling Instructions

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Trifluperidol hydrochloride is a Sigma-1 receptor antagonist with a K_i value of 3.3 nM. Trifluperidol hydrochloride is used in the study of psychosis.

For research use only. We do not sell to patients.

Trifluperidol hydrochloride Chemical Structure

CAS No. : 2062-77-3

Size	Price	Stock	Quantity
5 mg	USD 220	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Description

Trifluperidol hydrochloride is a Sigma-1 receptor antagonist with a K_i value of 3.3 nM. Trifluperidol hydrochloride is used in the study of psychosis^[1].

Molecular Weight

445.88

Formula

C₂₂H₂₄ClF₄NO₂

CAS No.

2062-77-3

Appearance

Solid

Color

White to off-white

SMILES

O=C(CCCN1CCC(O)(CC1)C2=CC=CC(C(F)(F)F)=C2)C3=CC=C(C=C3)F.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 40 mg/mL (89.71 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2428 mL	11.2138 mL	22.4276 mL
5 mM	0.4486 mL	2.2428 mL	4.4855 mL
10 mM	0.2243 mL	1.1214 mL	2.2428 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.4%

Select Batch:

Data Sheet (265 KB) SDS (479 KB)

COA (245 KB)

Handling Instructions (2659 KB)

References

[1]. Schetz JA, et al. A prototypical Sigma-1 receptor antagonist protects against brain ischemia. Brain Res. 2007 Nov 21;1181:1-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2428 mL	11.2138 mL	22.4276 mL	56.0689 mL
	5 mM	0.4486 mL	2.2428 mL	4.4855 mL	11.2138 mL
	10 mM	0.2243 mL	1.1214 mL	2.2428 mL	5.6069 mL
	15 mM	0.1495 mL	0.7476 mL	1.4952 mL	3.7379 mL
	20 mM	0.1121 mL	0.5607 mL	1.1214 mL	2.8034 mL
	25 mM	0.0897 mL	0.4486 mL	0.8971 mL	2.2428 mL
	30 mM	0.0748 mL	0.3738 mL	0.7476 mL	1.8690 mL
	40 mM	0.0561 mL	0.2803 mL	0.5607 mL	1.4017 mL
	50 mM	0.0449 mL	0.2243 mL	0.4486 mL	1.1214 mL
	60 mM	0.0374 mL	0.1869 mL	0.3738 mL	0.9345 mL
	80 mM	0.0280 mL	0.1402 mL	0.2803 mL	0.7009 mL

Trifluperidol hydrochloride Related Classifications

Neurological Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trifluperidol2062-77-3R 2498R2498R-2498Sigma ReceptorSigma-1 receptorAntagonistantipsychoticInhibitorinhibitorinhibit

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