Tryprostatin A

Cat. No.: HY-N7291: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Tryprostatin A is an inhibitor of the mammalian cell cycle. Tryprostatins A can be isolated from the secondary metabolites of a marine fungal strain BM939.

For research use only. We do not sell to patients.

Tryprostatin A Chemical Structure

CAS No. : 171864-80-5

Size		Stock
MOQ		Minimum order quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Tryprostatin A is an inhibitor of the mammalian cell cycle. Tryprostatins A can be isolated from the secondary metabolites of a marine fungal strain BM939^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
K562	IC₅₀	41 μM Compound: 13	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 19256529]
MCF7	GI₅₀	> 100 μM Compound: 1, tryprostatin A	Cytotoxicity against human MCF7 cells after 72 hrs by Cell Titer 96 Aqueous Non-Radioactive assay Cytotoxicity against human MCF7 cells after 72 hrs by Cell Titer 96 Aqueous Non-Radioactive assay	[PMID: 18321710]
PC-3	GI₅₀	94 μM Compound: 1, tryprostatin A	Cytotoxicity against human PC3 cells after 72 hrs by Cell Titer 96 Aqueous Non-Radioactive assay Cytotoxicity against human PC3 cells after 72 hrs by Cell Titer 96 Aqueous Non-Radioactive assay	[PMID: 18321710]

Molecular Weight

381.47

Formula

C₂₂H₂₇N₃O₃

CAS No.

171864-80-5

SMILES

O=C(N[C@H]1CC2=C(C/C=C(C)\C)NC3=C2C=CC(OC)=C3)[C@@](CCC4)([H])N4C1=O

Structure Classification

Initial Source

Microorganisms

Aspergillus fumigatus

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. CHENG-BIN CUI, et al. Tryprostatins A and B, Novel Mammalian Cell Cycle Inhibitors Produced by Aspergillus fumigatus. The Journal of Antibiotics. 1995, 48.

Tryprostatin A Related Classifications

Others

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tryprostatin A171864-80-5OthersNatural Products,Cell Cycle InhibitorInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks