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  4. TSQ

TSQ is a cytosolic zinc fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λmax ~470 nm). TSQ can combine with Zn2+ in the presence of Ca2+ and Mg2+ to produce blue fluorescence.

For research use only. We do not sell to patients.

TSQ Chemical Structure

TSQ Chemical Structure

CAS No. : 109628-27-5

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Based on 1 publication(s) in Google Scholar

TSQ Related Antibodies

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Description

TSQ is a cytosolic zinc fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λmax ~470 nm). TSQ can combine with Zn2+ in the presence of Ca2+ and Mg2+ to produce blue fluorescence[1].

In Vitro

The recommended working concentration of TSQ is 0.1 μM-10 μM.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

TSQ Related Antibodies
Molecular Weight

328.39

Formula

C17H16N2O3S
CAS No.
Appearance

Solid

Color

Light brown to brown

Emission (Em)

495
Excitation (Ex)

334
SMILES

O=S(C1=CC=C(C)C=C1)(NC2=C3N=CC=CC3=CC(OC)=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (304.52 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0452 mL 15.2258 mL 30.4516 mL
5 mM 0.6090 mL 3.0452 mL 6.0903 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0452 mL 15.2258 mL 30.4516 mL 76.1290 mL
5 mM 0.6090 mL 3.0452 mL 6.0903 mL 15.2258 mL
10 mM 0.3045 mL 1.5226 mL 3.0452 mL 7.6129 mL
15 mM 0.2030 mL 1.0151 mL 2.0301 mL 5.0753 mL
20 mM 0.1523 mL 0.7613 mL 1.5226 mL 3.8064 mL
25 mM 0.1218 mL 0.6090 mL 1.2181 mL 3.0452 mL
30 mM 0.1015 mL 0.5075 mL 1.0151 mL 2.5376 mL
40 mM 0.0761 mL 0.3806 mL 0.7613 mL 1.9032 mL
50 mM 0.0609 mL 0.3045 mL 0.6090 mL 1.5226 mL
60 mM 0.0508 mL 0.2538 mL 0.5075 mL 1.2688 mL
80 mM 0.0381 mL 0.1903 mL 0.3806 mL 0.9516 mL
100 mM 0.0305 mL 0.1523 mL 0.3045 mL 0.7613 mL
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TSQ Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TSQ109628-27-5Fluorescent DyezincInhibitorinhibitorinhibit

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