UDP-Galactose disodium

Name: UDP-Galactose disodium
Brand: MedChemExpress
SKU: HY-114364
Rating: 4.5 (1 reviews)

Cat. No.: HY-114364 Purity: 99.42%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

UDP-Galactose disodium is a natural agonist of the P2Y₁₄ receptor with an EC₅₀ of 0.67 μM for the hP2Y₁₄ receptor. UDP-Galactose disodium is a substrate for the transferase beta-1, 4 galactosyltransferase V (B4GALT5). In addition, UDP-Galactose disodium is required for the biosynthesis of several abundant glycoconjugates that form the surface glycocalyx of Leishmania major.

For research use only. We do not sell to patients.

UDP-Galactose disodium Chemical Structure

CAS No. : 137868-52-1

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
5 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 90	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 180	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 280	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 450	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of UDP-Galactose disodium:

UDP-α-D-Galactose-¹³C disodium Get quote
UDP-Galactose Get quote

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•Related Small Molecules:

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P2Y1 Receptor P2Y2 Receptor P2Y6 Receptor P2Y12 Receptor P2Y13 Receptor P2Y14 Receptor

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

P2Y14 Receptor

0.67 μM (EC₅₀)

Molecular Weight

610.27

Formula

C₁₅H₂₂N₂Na₂O₁₇P₂

CAS No.

137868-52-1

Appearance

Solid

Color

White to off-white

SMILES

O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(O[C@@H]3[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)(O[Na])=O)(O[Na])=O)O2)NC1=O

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 250 mg/mL (409.65 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6386 mL	8.1931 mL	16.3862 mL
5 mM	0.3277 mL	1.6386 mL	3.2772 mL
10 mM	0.1639 mL	0.8193 mL	1.6386 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.42%

Select Batch:

Data Sheet (274 KB) SDS (393 KB)

COA (252 KB) HNMR (274 KB) CNMR (296 KB) LCMS (99 KB)

Handling Instructions (2659 KB)

References

[1]. Ko H, et al. Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J Med Chem. 2007 May 3;50(9):2030-9. [Content Brief]

[2]. Drabavicius G, Daelemans D. Intermedilysin cytolytic activity depends on heparan sulfates and membrane composition. PLoS Genet. 2021 Feb 12;17(2):e1009387. [Content Brief]

[3]. Lamerz A C, et al. Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania major[J]. Glycobiology, 2010, 20(7): 872-882. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.6386 mL	8.1931 mL	16.3862 mL	40.9655 mL
	5 mM	0.3277 mL	1.6386 mL	3.2772 mL	8.1931 mL
	10 mM	0.1639 mL	0.8193 mL	1.6386 mL	4.0965 mL
	15 mM	0.1092 mL	0.5462 mL	1.0924 mL	2.7310 mL
	20 mM	0.0819 mL	0.4097 mL	0.8193 mL	2.0483 mL
	25 mM	0.0655 mL	0.3277 mL	0.6554 mL	1.6386 mL
	30 mM	0.0546 mL	0.2731 mL	0.5462 mL	1.3655 mL
	40 mM	0.0410 mL	0.2048 mL	0.4097 mL	1.0241 mL
	50 mM	0.0328 mL	0.1639 mL	0.3277 mL	0.8193 mL
	60 mM	0.0273 mL	0.1366 mL	0.2731 mL	0.6828 mL
	80 mM	0.0205 mL	0.1024 mL	0.2048 mL	0.5121 mL
	100 mM	0.0164 mL	0.0819 mL	0.1639 mL	0.4097 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.