2. Neuronal Signaling GPCR/G Protein Others
  3. Dopamine Receptor Others
  4. UNC9975

UNC9975 is a D2R agonist that displays signaling bias via β-arrestin–ergic signaling and a simultaneously antagonist of Gi-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9975 can be utilized in antipsychotic research.

For research use only. We do not sell to patients.

UNC9975 Chemical Structure

UNC9975 Chemical Structure

CAS No. : 1354030-19-5

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Description

UNC9975 is a D2R agonist that displays signaling bias via β-arrestin–ergic signaling and a simultaneously antagonist of Gi-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9975 can be utilized in antipsychotic research[1].

Molecular Weight

463.40

Formula

C23H28Cl2N4O2
CAS No.
SMILES

O=C1NC2=NC(OCCCCN3CCN(C4=CC=CC(Cl)=C4Cl)CCC3)=CC=C2CC1
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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UNC9975 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UNC99751354030-19-5UNC 9975UNC-9975Dopamine ReceptorOthersD2R agonistβ-arrestinantipsychoticInhibitorinhibitorinhibit

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