Upacicalcet

Cat. No.: HY-109106: FAQs
Data Sheet Handling Instructions

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Upacicalcet is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT).

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Upacicalcet sodium) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Upacicalcet Chemical Structure

CAS No. : 1333218-50-0

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This product is a controlled substance and not for sale in your territory.

Other Forms of Upacicalcet:

(Rac)-Upacicalcet Get quote
Upacicalcet sodium Get quote

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Description	Upacicalcet is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT)^[1].
IC₅₀ & Target	calcium-sensing receptors^[1]
Molecular Weight	351.76
Formula	C₁₁H₁₄ClN₃O₆S
CAS No.	1333218-50-0
SMILES	O=C(NC[C@H](N)C(O)=O)NC1=CC(S(=O)(O)=O)=CC(Cl)=C1C
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (266 KB) Handling Instructions (2659 KB)
References	[1]. Hoy SM. Upacicalcet: First Approval. Drugs. 2021;81(13):1593-1596. [Content Brief]

Upacicalcet Related Classifications

Endocrinology

Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Upacicalcet1333218-50-0CaSRCalcium-sensing receptorcalcium-sensing receptorscalcimimetic agentparathyroid hormonePTHsecondary hyperparathyroidismSHPTInhibitorinhibitorinhibit

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Upacicalcet

Other Forms of Upacicalcet:

Upacicalcet Related Antibodies

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