Upacicalcet sodium

Cat. No.: HY-109106A Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Upacicalcet sodium is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT).

For research use only. We do not sell to patients.

Upacicalcet sodium Chemical Structure

CAS No. : 2052969-18-1

Size	Price	Stock	Quantity
5 mg	USD 550	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 880	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 1750	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 2800	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 4500	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Upacicalcet sodium:

(Rac)-Upacicalcet Get quote
Upacicalcet Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

calcium-sensing receptors^[1]

Molecular Weight

373.75

Formula

C₁₁H₁₃ClN₃NaO₆S

CAS No.

2052969-18-1

Appearance

Solid

Color

White to off-white

SMILES

O=C(NC[C@H](N)C(O[Na])=O)NC1=CC(S(=O)(O)=O)=CC(Cl)=C1C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (267.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6756 mL	13.3779 mL	26.7559 mL
5 mM	0.5351 mL	2.6756 mL	5.3512 mL
10 mM	0.2676 mL	1.3378 mL	2.6756 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (248 KB) HNMR (161 KB) MS (175 KB)

Handling Instructions (2659 KB)

References

[1]. Hoy SM. Upacicalcet: First Approval. Drugs. 2021;81(13):1593-1596. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6756 mL	13.3779 mL	26.7559 mL	66.8896 mL
	5 mM	0.5351 mL	2.6756 mL	5.3512 mL	13.3779 mL
	10 mM	0.2676 mL	1.3378 mL	2.6756 mL	6.6890 mL
	15 mM	0.1784 mL	0.8919 mL	1.7837 mL	4.4593 mL
	20 mM	0.1338 mL	0.6689 mL	1.3378 mL	3.3445 mL
	25 mM	0.1070 mL	0.5351 mL	1.0702 mL	2.6756 mL
	30 mM	0.0892 mL	0.4459 mL	0.8919 mL	2.2297 mL
	40 mM	0.0669 mL	0.3344 mL	0.6689 mL	1.6722 mL
	50 mM	0.0535 mL	0.2676 mL	0.5351 mL	1.3378 mL
	60 mM	0.0446 mL	0.2230 mL	0.4459 mL	1.1148 mL
	80 mM	0.0334 mL	0.1672 mL	0.3344 mL	0.8361 mL
	100 mM	0.0268 mL	0.1338 mL	0.2676 mL	0.6689 mL