1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Uracil-13C4

Uracil-13C4 is the 13C labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].

For research use only. We do not sell to patients.

Uracil-<sup>13</sup>C<sub>4</sub> Chemical Structure

Uracil-13C4 Chemical Structure

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1 mg USD 100 In-stock
5 mg USD 250 In-stock
10 mg USD 410 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Uracil-13C4 is the 13C labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

116.04

Formula

13C4H4N2O2

Unlabeled CAS

66-22-8

Appearance

Solid

Color

White to off-white

SMILES

O=[13C]1[13C]=[13C]N[13C](N1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (215.44 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.6177 mL 43.0886 mL 86.1772 mL
5 mM 1.7235 mL 8.6177 mL 17.2354 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.00%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 8.6177 mL 43.0886 mL 86.1772 mL 215.4429 mL
5 mM 1.7235 mL 8.6177 mL 17.2354 mL 43.0886 mL
10 mM 0.8618 mL 4.3089 mL 8.6177 mL 21.5443 mL
15 mM 0.5745 mL 2.8726 mL 5.7451 mL 14.3629 mL
20 mM 0.4309 mL 2.1544 mL 4.3089 mL 10.7721 mL
25 mM 0.3447 mL 1.7235 mL 3.4471 mL 8.6177 mL
30 mM 0.2873 mL 1.4363 mL 2.8726 mL 7.1814 mL
40 mM 0.2154 mL 1.0772 mL 2.1544 mL 5.3861 mL
50 mM 0.1724 mL 0.8618 mL 1.7235 mL 4.3089 mL
60 mM 0.1436 mL 0.7181 mL 1.4363 mL 3.5907 mL
80 mM 0.1077 mL 0.5386 mL 1.0772 mL 2.6930 mL
100 mM 0.0862 mL 0.4309 mL 0.8618 mL 2.1544 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Uracil-13C4
Cat. No.:
HY-I0960S1
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